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Genetically Modified

The
Case for a GM-Free Sustainable World - A Summary
Independent Science
Panel Report Released 15 June 2003
Why
GM-Free?
- GM crops failed to deliver promised benefits
- No increase in yields or significant
reduction in
herbicide and pesticide use
- United States lost an estimated $12 billion
over
GM crops amid worldwide rejection
- Massive crop failures of up to 100%
reported in
India
- High risk future for agbiotech: "Monsanto
could
be another disaster waiting to happen for investors"
- GM crops posing escalating problems on the
farm
- Transgenic lines unstable: "most cases of
transgene inactivation never reach the literature"
- Triple herbicide-tolerant volunteers and
weeds
emerged in North America
- Glyphosate-tolerant weeds plague GM cotton
and
soya fields, atrazine back in use
- Bt biopesticide traits threatening to
create
superweeds and bt-resistant pests
- Extensive transgenic contamination
unavoidable
- Extensive transgenic contamination found in
maize
landraces in remote regions of Mexico
- 32 out of 33 commercial seed stocks found
contaminated in Canada
- Pollen remains airborne for hours, and a 35
mile
per hour wind speed is unexceptional
- There can be no co-existence of GM and
non-GM
crops
- GM crops not safe
- GM crops have not been proven safe:
regulation
was fatally flawed from the start
- The principle of 'substantial equivalence',
vague
and ill defined, gave companies complete licence in claiming GM
products 'substantially equivalent' to non-GM, and hence 'safe'
- GM food raises serious safety concerns
- Despite the paucity of credible studies,
existing
findings raise serious safety concerns
- 'Growth-factor-like' effects in the stomach
and
small intestine of young rats were attributed to the transgenic process
or the transgenic construct, and may hence be general to all GM food
- Dangerous gene products are incorporated
into food
crops
- Bt proteins, incorporated into 25% of all
GM
crops worldwide, are harmful to many non-target insects, and some are
potent immunogens and allergens for humans and other mammals
- Food crops are increasingly used to produce
pharmaceuticals and drugs, including cytokines known to suppress the
immune system, or linked to dementia, neurotoxicity and mood and
cognitive side effects; vaccines and viral sequences such as the
'spike' protein gene of the pig coronavirus, in the same family as the
SARS virus linked to the current epidemic; and glycoprotein gene gp120
of the AIDS virus that could interfere with the immune system and
recombine with viruses and bacteria to generate new and unpredictable
pathogens.
- Terminator crops spread male sterility
- Crops engineered with 'suicide' genes for
male
sterility, promoted as a means of preventing the spread of transgenes,
actually spread both male sterility and herbicide tolerance traits via
pollen.
- Broad-spectrum herbicides highly toxic to
humans
and other species
- Glufosinate ammonium and glyphosate, used
with
herbicide tolerant GM crops that currently account for 75% of all GM
crops worldwide, are both systemic metabolic poisons
- Glufosinate ammonium is linked to
neurological,
respiratory, gastrointestinal and haematological toxicities, and birth
defects in humans and mammals; also toxic to butterflies and a number
of beneficial insects, to larvae of clams and oysters, Daphnia
and some freshwater fish, especially the rainbow trout; it inhibits
beneficial soil bacteria and fungi, especially those that fix nitrogen.
- Glyphosate is the most frequent cause of
complaints and poisoning in the UK, and disturbances to many body
functions have been reported after exposures at normal use levels;
glyphosate exposure nearly doubled the risk of late spontaneous
abortion, and children born to users of glyphosate had elevated
neurobehavioral defects; glyphosate retards development of the foetal
skeleton in laboratory rats, inhibits the synthesis of steroids, and is
genotoxic in mammals, fish and frogs; field dose exposure of earthworms
caused at least 50 percent mortality and significant intestinal damage
among surviving worms; Roundup (Monsanto's formulation of glyphosate)
caused cell division dysfunction that may be linked to human cancers.
- Genetic engineering creates super-viruses
- The most insidious dangers of genetic
engineering
are inherent to the process; it greatly enhances the scope and
probability of horizontal gene transfer and recombination, the main
route to creating viruses and bacteria that cause disease epidemics.
- Newer techniques, such as DNA shuffling,
allow
geneticists to create in a matter of minutes in the laboratory millions
of recombinant viruses that have never existed in billions of years of
evolution
- Disease-causing viruses and bacteria and
their
genetic material are the predominant materials and tools of genetic
engineering, as much as for the intentional creation of bio-weapons.
- Transgenic DNA in food taken up by bacteria
in
human gut
- Transgenic DNA from plants has been taken
up by
bacteria both in the soil and in the gut of human volunteers;
antibiotic resistance marker genes can spread from transgenic food to
pathogenic bacteria, making infections very difficult to treat.
- Transgenic DNA and cancer
- Transgenic DNA known to survive digestion
in the
gut and to jump into the genome of mammalian cells, raising the
possibility for triggering cancer
- Feeding GM products such as maize to
animals may
carry risks, not just for the animals but also for human beings
consuming the animal products
- CaMV 35S promoter increases horizontal gene
transfer
- Evidence suggests that transgenic
constructs with
the CaMV 35S promoter could be especially unstable and prone to
horizontal gene transfer and recombination, with all the attendant
hazards: gene mutations due to random insertion, cancer, re-activation
of dormant viruses and generation of new viruses.
- A history of misrepresentation and
suppression of
scientific evidence
- There has been a history of
misrepresentation and
suppression of scientific evidence, especially on horizontal gene
transfer. Key experiments failed to be performed, or were performed
badly and then misrepresented. Many experiments were not followed up,
including investigations on whether the CaMV 35S promoter is
responsible for the 'growth-factor-like' effects observed in young rats
fed GM potatoes.
GM
crops have failed to deliver the promised benefits and are posing
escalating problems on the farm. Transgenic contamination is now widely
acknowledged to be unavoidable, and hence there can be no co-existence
of GM and non-GM agriculture. Most important of all, GM crops have not
been proven safe. On the contrary, sufficient evidence has emerged to
raise serious safety concerns, that if ignored could result in
irreversible damage to health and the environment. GM crops should
therefore be firmly rejected now.
Why
Sustainable Agriculture?
- Higher productivity and yields especially in
the
Third World
- 8.98 million farmers adopted sustainable
agriculture practices on 28.92 million hectares in Asia, Latin America
and Africa; reliable data from 89 projects show higher productivity and
yields: 50-100% increase in yield for rainfed crops, and 5-10% for
irrigated crops; top successes include Burkina Faso, which turned a
cereal deficit of 644 kg per year to an annual surplus of 153 kg,
Ethiopia, where 12 500 households enjoyed 60% increase in crop yields,
and Honduras and Guatemala, where 45 000 families increased yields from
400-600 kg/ha to 2,000-2,500 kg/ha
- Long-term studies in industrialised
countries
show yields for organic comparable to conventional agriculture, and
often higher
- Better soils
- Sustainable agricultural practices reduce
soil
erosion, improve soil physical structure and water-holding capacity,
which are crucial in averting crop failures during periods of drought
- Soil fertility maintained or increased by
various
sustainable agriculture practices
- Biological activity higher in organic
soils: more
earthworms, arthropods, mycorrhizal and other fungi, and
micro-organisms, all beneficial for nutrient recycling and suppression
of disease
- Cleaner environment
- Little or no polluting chemical inputs with
sustainable agriculture
- Less nitrate and phosphorus leached to
groundwater from organic soils
- Better water infiltration rates in organic
systems, therefore less prone to erosion and less likely to contribute
to water pollution from surface runoff
- Reduced pesticides and no increase in pests
- Integrated pest management cut the
number of
pesticide sprays in Vietnam from 3.4 to one per season, in Sri Lanka
from 2.9 to 0.5 per season, and in Indonesia from 2.9 to 1.1 per season
- No increase in crop losses due to pest
damage
resulted from withdrawal of synthetic insecticides in Californian
tomato production
- Pest control achievable without pesticides,
reversing crop losses, as for example, by using 'trap crops' to attract
stem borer, a major pest in East Africa
- Supporting biodiversity and using diversity
- Sustainable agriculture promotes
agricultural
biodiversity, which is crucial for food security; organic farming can
support much greater biodiversity, benefiting species that have
significantly declined
- Integrated farming systems in Cuba are 1.45
to
2.82 times more productive than monocultures
- Thousands of Chinese rice farmers doubled
yields
and nearly eliminated the most devastating disease simply by mixed
planting of two varieties
- Soil biodiversity enhanced by organic
practices,
bringing beneficial effects such as recovery and rehabilitation of
degraded soils, improved soil structure and water infiltration.
- Environmentally and economically sustainable
- Research on apple production systems ranked
the
organic system first in environmental and economic sustainability, the
integrated system second and the conventional system last; organic
apples were most profitable due to price premiums, quicker investment
return, and fast recovery of costs
- A Europe-wide study showed that organic
farming
performs better than conventional farming in the majority of
environmental indicators
- A review by the United Nations Food and
Agriculture Organization (FAO) concluded that well-managed organic
agriculture leads to more favourable conditions at all environmental
levels
- Ameliorating climate change by reducing
direct
& indirect energy use
- Organic agriculture uses energy much more
efficiently and greatly reduces CO2 emissions compared with
conventional agriculture, both with respect to direct energy
consumption in fuel and oil and indirect consumption in synthetic
fertilizers and pesticides
- Sustainable agriculture restores soil
organic
matter content, increasing carbon sequestration below ground, thereby
recovering an important carbon sink
- Organic agriculture is likely to emit less
nitrous dioxide (N2O), another important greenhouse gas and
also a cause of stratospheric ozone depletion
- Efficient, profitable production
- Any yield reduction in organic agriculture
more
than offset by ecological and efficiency gains
- Smaller farms produce far more per unit
area than
larger farms characteristic of conventional farming
- Production costs for organic farming are
often
lower than conventional farming, bringing equivalent or higher net
returns even without organic price premiums; when price premiums are
factored in, organic systems are almost always more profitable
- Improved food security and benefits to local
communities
- A review of sustainable agriculture
projects
showed that average food production per household increased by 1.71
tonnes per year (up 73%) for 4.42 million farmers on 3.58 million
hectares, bringing food security and health benefits to local
communities
- Increasing productivity increases food
supplies
and raises incomes, thereby reducing poverty, increasing access to
food, reducing malnutrition and improving health and livelihoods
- Sustainable agricultural approaches draw
extensively on traditional and indigenous knowledge, and place emphasis
on the farmers' experience and innovation, thereby improving their
status and autonomy, enhancing social and cultural relations within
local communities
- For every £1 spent at an organic box
scheme
from Cusgarne Organics (UK), £2.59 is generated for the local
economy; but for every £1 spent at a supermarket, only
£1.40 is generated for the local economy
- Better food quality for health
- Organic food is safer, as organic farming
prohibits pesticide use, so harmful chemical residues are rarely found
- Organic production bans the use of
artificial
food additives, such as hydrogenated fats, phosphoric acid, aspartame
and monosodium glutamate, which have been linked to health problems as
diverse as heart disease, osteoporosis, migraines and hyperactivity
- Studies have shown that on average, organic
food
has higher vitamin C, higher mineral levels and higher plant phenolics
- plant compounds that can fight cancer and heart disease, and combat
age-related neurological dysfunctions - and significantly less
nitrates, a toxic compound.
Sustainable
agricultural practices have proven beneficial in all aspects relevant
to health and the environment. In addition, they bring food security
and social and cultural well being to local communities everywhere.
There is an urgent need for a comprehensive global shift to all forms
of sustainable agriculture.
To
learn more about
the
Independent Science Panel, scientists involved, and their 120 page
final report please visit: http://www.i-sis.org.uk.
If
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Independent Science Panel Members
From http://www.i-sis.org.uk
Prof.
Miguel Altieri
Professor of Agroecology, University of California, Berkeley, USA
Dr.
Michael Antoniou
Senior Lecturer in Molecular Genetics, GKT School of Medicine, King's
College, London.
Dr.
Susan Bardocz
Biochemist, formerly Rowett Research Institute, Scotland
Prof.
David Bellamy OBE
Internationally renowned botanist, environmentalist, broadcaster,
author and campaigner; recipient of number awards; President & Vice
President of many conservation and environmental organisations.
Dr.
Elizabeth Bravo V.
Biologist, researcher and campaigner on biodiversity and GMO issues;
co-founder of Acción Ecológica; part-time lecturer at
Universidad Politécnica Salesiana, Ecuador.
Prof.
Joe Cummins
Professor Emeritus of Genetics, University of Western Ontario, London,
Ontario, Canada.
Dr.
Stanley Ewen
Consultant Histopathologist at Grampian University Hospitals Trust;
formerly Senior Lecturer in Pathology, University of Aberdeen; lead
histopathologist for the Grampian arm of the Scottish Colorectal Cancer
Screening Pilot Project.
Edward
Goldsmith
Recipient of the Right Livelihood and numerous awards,
environmentalist, scholar, author and Founding Editor of The Ecologist.
Dr.
Brian Goodwin
Scholar in Residence, Schumacher College, England.
Dr.
Mae-Wan Ho
Co-founder and Director of the Institute of Science in Society; Editor
of Science in Society; Science Advisor to the Third World Network and
on the Roster of Experts for the Cartagena Protocol on Biosafety;
Visiting Reader, Open University, UK and Visiting Professor of Organic
Physics, Catania University, Sicily, Italy.
Prof.
Malcolm Hooper
Emeritus Professor at the University of Sunderland; previously,
Professor of Medicinal Chemistry, Faculty of Pharmaceutical Sciences,
Sunderland Polytechnic; Chief Scientific Advisor to the Gulf War
Veterans.
Dr.
Vyvyan Howard
Medically qualified toxico-pathologist, Developmental Toxico-Pathology
Group, Department of Human Anatomy and Cell Biology, The University of
Liverpool; Member of the UK Government's Advisory Committee on
Pesticides.
Dr.
Brian John
Geomorphologist and environmental scientist; Founder and long-time
Chairman of the West Wales Eco Centre; one of the coordinating group of
GM Free Cymru
Prof.
Marijan Jošt
Professor of Plant Breeding and Seed Production, Agricultural College
Križevci, Croatia.
Lim
Li Ching
Researcher, Institute of Science in Society and Third World Network;
deputy-editor of Science in Society.
Dr.
Eva Novotny
Astronomer and campaigner on GM issues for Scientists for Global
Responsibility, SGR
Prof.
Bob Orskov OBE
Head of the International Feed Resource Unit in Macaulay Institute,
Aberdeen, Scotland; Fellow of the Royal Society of Edinburgh, FRSE;
Fellow of the Polish Academy of Science.
Dr.
Michel Pimbert
Agricultural ecologist and Principal Associate, International Institute
for Environment and Development.
Dr.
Arpad Pusztai
Private consultant; formerly Senior Research Fellow at the Rowett
Research Institute, Aberdeen, Scotland.
David
Quist
Microbial ecologist, Ecosystem Science Division, Environmental Science,
Policy and Management, University of California, Berkeley, USA.
Dr.
Peter Rosset
Agricultural ecologist and rural development specialist; Co-director of
the Institute for Food and Development Policy (Food First), Oakland,
California, USA.
Prof.
Peter Saunders
Professor of Applied Mathematics at King's College, London.
Dr.
Veljko Veljkovic
AIDS virologist, Center for Multidisciplinary Research and Engineering,
Institute of Nuclear Sciences, VINCA, Belgrade, Yugoslavia.
Roberto
Verzola
Secretary-General, Philippine Greens, Member of the Board of Trustees,
PABINHI (a sustainable agriculture network), Coordinator, SRI-Pilipinas
(network of advocates for the System of Rice Intensification).
Prof.
Oscar B. Zamora
Professor of Agronomy, Department of Agronomy, University of the
Philippines Los Banos-College of Agriculture (UPLB-CA), College,
Laguna, The Philippines.
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